A mild form of Parkinsons can cause severe damage to the brain

Sixteen protein proteins were identified as crucial components in the dysregulated communication that causes Parkinsons Disease advance. Such dysregulated communication is a hallmark of development of the disease but researchers say the findings point to new ways to protect against this damage in diseased brainsPeer reviewed papers with information about the clinical characteristics of patients with Parkinsons Disease or a mild form of the disease are available on the Salk website. Scientists at UC San Diego School of Biological Sciences in collaboration with collaborators at the University of Groningen have built a comprehensive searchable database to map the roles of 52 proteins within the nervous system that play key roles in cellular communication. We manage to eliminate a lot of silencing of these silencing factors by which we translate this tremendous knowledge into new techniques and directions mostly in the brain said senior author Yoshinori Yanamoto MD associate professor of Neurology and senior investigator on the Salk clinical and translational research efforts. And whats really exciting at this point is that the list is so large it actually has data all the way down to the individual hairs the individual proteins that are already implicated in progress in development of Parkinsons Disease.

Patients with the mild form of Parkinsons Disease may be more vulnerable to severe damage and cognitive impairment than those in the more severe forms of the disease according to a Salk scientists who are exploring new approaches to preventing and treating the brain injuries that are symptoms of Parkinsons Disease. The scientists developed a new mouse model to shed light on the underlying mechanism of Parkinsons Disease while shepherding researchers to start testing drugs for personalized treatments for both forms. The study appears in the journal Science Translational Medicine.